Inclusion criteria were: age > 18 and ≤ 75 years, admitted to ICU with confirmed COVID-19-related pneumonia, receiving supplemental oxygen (standard oxygen therapy or high-flow nasal cannula (HFNC)) for 3 h (ranged from 3 to 5.8 h without interruption) before being returned to the supine position. In this study, we assessed the effect of prone position on V/Q matching using electrical impedance tomography (EIT) in non-intubated COVID-19 patients. Whether awake prone positioning can improve ventilation/perfusion (V/Q) matching through redistribution of pulmonary perfusion has not been demonstrated. In the early phase of COVID-19, hypoxemia may be caused by impaired regulation of pulmonary perfusion. It is also a mainstay of treatment in COVID-19-related ARDS (C-ARDS) and reduces the need for intubation without any signal of harm.
Prone positioning may recruit gas exchange-efficient regions for typical acute respiratory distress syndrome (ARDS) and improve oxygenation.
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